Biological
Female sex
Atopic dermatitis
Childhood eczema
Low age at onset of hand eczema
Genetic mutations
Contact allergy
You know it’s chronic hand eczema (CHE) when the eczema on your patients’ hands and wrists has
lasted for
MORE THAN
3 MONTHS1
relapsed
MORE THAN
TWICE A YEAR1
Chronic hand eczema is not an uncommon skin disease, with an overall self-reported physician-diagnosed prevalence of 4.7% in the general population.2,3
Patients with CHE may present with multiple subtypes, including atopic dermatitis.1
Chronic hand eczema expresses itself in a language all its own, with signs and symptoms that include4
Biological
Female sex
Atopic dermatitis
Childhood eczema
Low age at onset of hand eczema
Genetic mutations
Contact allergy
Environmental
Wet work
Occupational or domestic exposure (prolonged exposure to irritants)
Climate (cold/dry conditions)
Lifestyle
Tobacco use
Stress
“When there are cracks, even at work and all, it also hurts when you move the hands.”
— Patient with CHE8
CHE negatively impacts patients’ quality of life, often bringing on5,9
Anxiety
Low self-esteem
Social phobia
Embarrassment
Self-isolation
76%...reported it affected their social or leisure activities
38%...felt it impacted their engagement in activities
79%...stated it had a negative effect on their mood
“If my hands and fingers clear up completely, then I will be able to play the guitar again.”
— Patient with CHE8
References: 1. Thyssen JP, et al. Contact Dermatitis. 2022;86(5):357-378. doi:10.1111/cod.14035 2. Lee GR, et al. Dermatol Ther. 2019;32(3):e12840. doi:10.1111/dth.12840 3. Apfelbacher C, et al. Prevalence of chronic hand eczema in adults: A cross sectional multi-national study of over 60,000 respondence in the general population. Poster presented at: The Congress of the European Society of Contact Dermatitis (ESCD); September 4-7, 2024; Dresden, Germany. 4. Grant L, et al. Adv Ther. 2020;37(2):692-706. doi:10.1007/s12325-019-01164-5 5. Lynde C, et al. J Cutan Med Surg. 2010;14(6):267-284. doi:10.2310/7750.2010.09094 6. Mirabelli MC, et al. Contact Dermatitis. 2012;66(4):188-196. doi:10.1111/j.1600-0536.2011.02023.x 7. Dubin C, et al. Ther Clin Risk Manag. 2020;16:1319-1332. doi:10.2147/TCRM.S292504 8. Rönsch H, et al. J Eur Acad Dermatol Venereol. 2023;37(7):1396-1405. doi:10.1111/jdv.19055 9. Agner T, et al. J Eur Acad Dermatol Venereol. 2020;34(suppl 1):4-12. doi:10.1111/jdv.16061 10. Ahmed A, et al. Clin Exp Dermatol. 2015;40(5):495-501. doi:10.1111/ced.12619